basic fibroblast growth factor การใช้

• This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.
• Basic fibroblast growth factor has been shown to interact with casein kinase 2, alpha 1, RPL6 and ribosomal protein S19.
• This particular family member binds both acidic and basic fibroblast growth factor and plays a role in bone development and maintenance.
• This drug delivery system has been used extensively to deliver growth factors with a high affinity for heparin, such as basic fibroblast growth factor.
• Other healing-associated growth factors produced by platelets include basic fibroblast growth factor, insulin-like growth factor 1, platelet-derived epidermal growth factor, and vascular endothelial growth factor.
• What broke the treatment impasse was Folkman's suggestion that Jennifer's blood be tested for the presence of a protein called basic fibroblast growth factor ( basic FGF ).
• The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression.
• VEGF promotes angioblast differentiation; whereas, VEGFR-1 stops the hemangioblast from becoming an EC . In addition, basic fibroblast growth factor FGF-2 is also involved in promoting angioblasts from the mesoderm.
• Alpha-2-macroglobulin may act as a carrier protein because it also binds to numerous growth factors and cytokines, such as platelet-derived growth factor, basic fibroblast growth factor, TGF-?, insulin, and IL-1?.
• Some peptide / protein hormones ( angiotensin II, basic fibroblast growth factor-2, parathyroid hormone-related protein ) also interact with intracellular receptors located in the cytoplasm or nucleus by an intracrine mechanism.
• In vitro studies have shown that AMG 706 inhibits human endothelial cell proliferation induced by VEGF, but not by basic fibroblast growth factor, as well as vascular permeability induced by VEGF in mice.
• He points out that other substances which repair neurons _ such as nerve growth factor and basic fibroblast growth factor _ have been shown to repair axons, the fibers that transmit nerve signals.
• Acidic and basic fibroblast growth factor, neurotrophin 3, transforming growth factor beta 1, transforming growth factor beta 2, nerve growth factor, brain derived neurotrophic factor can be given as examples for such growth factors.
• The Mountain View, California-based company said Wednesday the U . S . Patent and Trademark Office issued it a patent covering the method of making human basic fibroblast growth factor by recombinant DNA techniques.
• It has been shown to directly interact with the human securin and proto-oncogene, PTTG1, thus facilitating its nuclear translocation and the subsequent transcriptional activation of basic fibroblast growth factor ( bFGF ) by PTTG1.
• Endostatin is a broad-spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors such as basic fibroblast growth factor ( bFGF / FGF-2 ) and vascular endothelial growth factor ( VEGF ).
• As well as blocking a protein involved in blood vessel growth called vascular endothelial growth factor, the new drug also interferes with two other blood vessel growth factors _ basic fibroblast growth factor and platelet-derived growth factor.
• There are five growth factors that have been shown to be significantly upregulated and active during tendon healing : insulin-like growth factor 1 ( IGF-I ), platelet-derived growth factor ( PDGF ), vascular endothelial growth factor ( VEGF ), basic fibroblast growth factor ( bFGF ), and transforming growth factor beta ( TGF-? ).